@import url("https://fonts.googleapis.com/css2?family=DM+Sans:wght@300;400;500;600&display=swap");

:root {
  color-scheme: dark;
  --ink: #030914;
  --paper: #f5f3ef;
  --muted: rgba(239, 244, 250, 0.68);
  --line: rgba(255, 255, 255, 0.18);
  --red: #e3293f;
  --ease: cubic-bezier(0.16, 1, 0.3, 1);
}

* {
  box-sizing: border-box;
}

html {
  scroll-behavior: smooth;
  background: var(--ink);
}

section[id] {
  scroll-margin-top: 1rem;
}

body {
  margin: 0;
  min-width: 320px;
  color: var(--paper);
  background: var(--ink);
  font-family: "DM Sans", Arial, sans-serif;
  -webkit-font-smoothing: antialiased;
}

body.menu-open {
  overflow: hidden;
}

a {
  color: inherit;
  text-decoration: none;
}

.skip-link {
  position: fixed;
  z-index: 100;
  top: 1rem;
  left: 1rem;
  padding: 0.75rem 1rem;
  color: #05070b;
  background: #fff;
  transform: translateY(-150%);
}

.skip-link:focus {
  transform: translateY(0);
}

.hero {
  position: relative;
  isolation: isolate;
  display: grid;
  min-height: 100svh;
  overflow: clip;
  background: #020812;
}

.hero__backdrop,
.hero__image,
.hero__veil,
.hero__aurora,
.hero__particles,
.hero__grain {
  position: absolute;
  inset: 0;
}

.hero__backdrop {
  z-index: -1;
  overflow: hidden;
  transform: scale(1.035);
  animation: scene-in 2.2s var(--ease) forwards;
}

.hero__image {
  background-image: url("./assets/astellas-hero.webp");
  background-position: center;
  background-size: cover;
  filter: saturate(0.86) contrast(1.05);
  transform: translate3d(var(--parallax-x, 0), var(--parallax-y, 0), 0) scale(1.045);
  transition: transform 1.2s var(--ease);
}

.hero__veil {
  background:
    linear-gradient(90deg, rgba(2, 8, 18, 0.96) 0%, rgba(2, 8, 18, 0.82) 25%, rgba(2, 8, 18, 0.22) 57%, rgba(2, 8, 18, 0.08) 78%),
    linear-gradient(180deg, rgba(2, 8, 18, 0.52) 0%, transparent 35%, rgba(2, 8, 18, 0.38) 100%);
}

.hero__aurora {
  opacity: 0.52;
  background: radial-gradient(circle at var(--glow-x, 61%) var(--glow-y, 47%), rgba(232, 37, 62, 0.2), transparent 9%);
  mix-blend-mode: screen;
  transition: background-position 500ms ease;
}

.hero__particles {
  width: 100%;
  height: 100%;
  opacity: 0.58;
}

.hero__grain {
  pointer-events: none;
  opacity: 0.12;
  background-image: url("data:image/svg+xml,%3Csvg viewBox='0 0 180 180' xmlns='http://www.w3.org/2000/svg'%3E%3Cfilter id='n'%3E%3CfeTurbulence type='fractalNoise' baseFrequency='.9' numOctaves='3' stitchTiles='stitch'/%3E%3C/filter%3E%3Crect width='100%25' height='100%25' filter='url(%23n)' opacity='.35'/%3E%3C/svg%3E");
  mix-blend-mode: soft-light;
}

.hero__pulse {
  position: absolute;
  z-index: 1;
  top: 46%;
  left: 61.2%;
  width: 1px;
  height: 1px;
  pointer-events: none;
}

.hero__pulse::before,
.hero__pulse::after,
.hero__pulse-core {
  position: absolute;
  inset: 50% auto auto 50%;
  display: block;
  width: 80px;
  aspect-ratio: 1;
  border: 1px solid rgba(255, 85, 105, 0.4);
  border-radius: 50%;
  content: "";
  transform: translate(-50%, -50%) scale(0.15);
  animation: pulse 3.4s ease-out infinite 1.6s;
}

.hero__pulse::after {
  animation-delay: 2.75s;
}

.hero__pulse-core {
  width: 10px;
  border: 0;
  background: #fff;
  box-shadow: 0 0 9px 3px #fff, 0 0 32px 14px rgba(238, 39, 64, 0.86), 0 0 90px 36px rgba(238, 39, 64, 0.35);
  transform: translate(-50%, -50%);
  animation: core-breathe 2.8s ease-in-out infinite;
}

.nav {
  position: absolute;
  z-index: 10;
  top: 0;
  left: 0;
  display: flex;
  align-items: center;
  justify-content: space-between;
  width: 100%;
  padding: 2rem clamp(1.5rem, 5vw, 5rem);
  opacity: 0;
  animation: fade-down 1s var(--ease) 0.25s forwards;
}

.brand {
  position: relative;
  display: inline-flex;
  align-items: baseline;
  gap: 0.5rem;
  letter-spacing: -0.045em;
}

.brand__name {
  font-size: clamp(1.5rem, 2.1vw, 2rem);
  font-weight: 500;
}

.brand__descriptor {
  color: rgba(255, 255, 255, 0.55);
  font-size: 0.56rem;
  font-weight: 600;
  letter-spacing: 0.18em;
}

.brand__star {
  position: absolute;
  top: -0.48rem;
  left: 1.65rem;
  width: 1.9rem;
  height: 0.65rem;
  border-top: 2px solid var(--red);
  border-radius: 50%;
  transform: rotate(-9deg);
}

.brand__star::after {
  position: absolute;
  top: -0.24rem;
  right: -0.08rem;
  width: 0.4rem;
  height: 0.4rem;
  border-radius: 50%;
  background: var(--red);
  content: "";
  box-shadow: 0 0 12px rgba(227, 41, 63, 0.85);
}

.nav__links {
  display: flex;
  gap: clamp(1.4rem, 3vw, 3rem);
  margin-left: auto;
  margin-right: 3rem;
  color: rgba(255, 255, 255, 0.74);
  font-size: 0.82rem;
}

.nav__links a {
  position: relative;
  transition: color 250ms ease;
}

.nav__links a::after {
  position: absolute;
  right: 0;
  bottom: -0.55rem;
  left: 0;
  height: 1px;
  background: var(--red);
  content: "";
  transform: scaleX(0);
  transform-origin: right;
  transition: transform 400ms var(--ease);
}

.nav__links a:hover,
.nav__links a:focus-visible {
  color: #fff;
}

.nav__links a:hover::after,
.nav__links a:focus-visible::after {
  transform: scaleX(1);
  transform-origin: left;
}

.nav__menu {
  display: grid;
  place-content: center;
  gap: 6px;
  width: 46px;
  height: 46px;
  padding: 0;
  border: 1px solid var(--line);
  border-radius: 50%;
  color: #fff;
  background: rgba(255, 255, 255, 0.03);
  cursor: pointer;
  transition: border-color 250ms ease, background 250ms ease;
}

.nav__menu:hover {
  border-color: rgba(255, 255, 255, 0.45);
  background: rgba(255, 255, 255, 0.08);
}

.nav__menu span {
  display: block;
  width: 16px;
  height: 1px;
  background: currentColor;
  transition: transform 350ms var(--ease);
}

.menu-open .nav__menu span:first-child { transform: translateY(3.5px) rotate(45deg); }
.menu-open .nav__menu span:last-child { transform: translateY(-3.5px) rotate(-45deg); }

.menu-panel {
  position: fixed;
  z-index: 8;
  inset: 0;
  display: flex;
  visibility: hidden;
  flex-direction: column;
  justify-content: center;
  padding: 8rem clamp(1.5rem, 8.3vw, 8rem) 3rem;
  background: rgba(2, 8, 18, 0.94);
  opacity: 0;
  backdrop-filter: blur(30px);
  transform: translateY(-18px);
  transition: opacity 450ms var(--ease), transform 450ms var(--ease), visibility 450ms;
}

.menu-open .menu-panel {
  visibility: visible;
  opacity: 1;
  transform: translateY(0);
}

.menu-panel__inner {
  display: flex;
  flex-direction: column;
  max-width: 760px;
}

.menu-panel__inner > p,
.menu-panel__foot {
  color: rgba(255, 255, 255, 0.42);
  font-size: 0.65rem;
  letter-spacing: 0.18em;
  text-transform: uppercase;
}

.menu-panel__inner > p { margin: 0 0 2rem; }

.menu-panel__inner a {
  display: flex;
  align-items: baseline;
  gap: 1.5rem;
  padding: 0.55rem 0;
  color: rgba(255, 255, 255, 0.72);
  font-size: clamp(2.5rem, 6vw, 5.8rem);
  font-weight: 300;
  letter-spacing: -0.06em;
  transition: color 250ms ease, transform 350ms var(--ease);
}

.menu-panel__inner a:hover { color: #fff; transform: translateX(10px); }
.menu-panel__inner a span { color: var(--red); font-size: 0.65rem; letter-spacing: 0; }
.menu-panel__foot { position: absolute; right: clamp(1.5rem, 5vw, 5rem); bottom: 2rem; }

.hero__content {
  align-self: center;
  width: min(650px, 46vw);
  margin-left: clamp(1.5rem, 8.3vw, 8rem);
  padding: 8rem 0 6rem;
}

.eyebrow {
  display: flex;
  align-items: center;
  gap: 0.8rem;
  margin: 0 0 1.7rem;
  color: rgba(255, 255, 255, 0.7);
  font-size: 0.68rem;
  font-weight: 600;
  letter-spacing: 0.2em;
  text-transform: uppercase;
  opacity: 0;
  animation: rise-in 900ms var(--ease) 0.55s forwards;
}

.eyebrow span {
  width: 2rem;
  height: 1px;
  background: var(--red);
  box-shadow: 0 0 10px rgba(227, 41, 63, 0.75);
}

h1 {
  max-width: 700px;
  margin: 0;
  font-size: clamp(3.4rem, 6.5vw, 7.4rem);
  font-weight: 300;
  letter-spacing: -0.068em;
  line-height: 0.91;
}

.title-line {
  display: block;
  overflow: hidden;
  padding-bottom: 0.1em;
}

.title-line > span {
  display: block;
  transform: translateY(112%);
  animation: title-reveal 1.15s var(--ease) 0.72s forwards;
}

.title-line--accent {
  margin-top: -0.02em;
  color: rgba(247, 247, 245, 0.72);
}

.title-line--accent > span {
  animation-delay: 0.87s;
}

.hero__lede {
  max-width: 510px;
  margin: 2rem 0 0;
  color: var(--muted);
  font-size: clamp(1rem, 1.18vw, 1.2rem);
  font-weight: 300;
  line-height: 1.62;
  opacity: 0;
  transform: translateY(16px);
  animation: rise-in 1s var(--ease) 1.16s forwards;
}

.hero__actions {
  display: flex;
  align-items: center;
  gap: 2rem;
  margin-top: 2.2rem;
  opacity: 0;
  transform: translateY(16px);
  animation: rise-in 1s var(--ease) 1.34s forwards;
}

.button {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  gap: 1.2rem;
  font-size: 0.82rem;
  font-weight: 500;
}

.button--primary {
  min-width: 200px;
  min-height: 58px;
  padding: 0.8rem 1.3rem 0.8rem 1.55rem;
  border: 1px solid rgba(255, 255, 255, 0.25);
  border-radius: 999px;
  background: rgba(255, 255, 255, 0.07);
  box-shadow: inset 0 1px 0 rgba(255, 255, 255, 0.1);
  backdrop-filter: blur(14px);
  transition: color 350ms ease, background 350ms ease, border-color 350ms ease, transform 350ms var(--ease);
}

.button--primary:hover,
.button--primary:focus-visible {
  color: #fff;
  border-color: var(--red);
  background: rgba(227, 41, 63, 0.9);
  transform: translateY(-2px);
}

.button__arrow {
  display: grid;
  place-items: center;
  width: 30px;
  height: 30px;
  margin-left: auto;
  border-radius: 50%;
  color: #13151a;
  background: #fff;
  font-size: 0.85rem;
}

.button--text {
  position: relative;
  color: rgba(255, 255, 255, 0.7);
  transition: color 250ms ease;
}

.button--text:hover,
.button--text:focus-visible {
  color: #fff;
}

.hero__meta {
  position: absolute;
  right: clamp(1.5rem, 5vw, 5rem);
  bottom: 2.25rem;
  display: flex;
  align-items: center;
  gap: 0.8rem;
  color: rgba(255, 255, 255, 0.46);
  font-size: 0.58rem;
  font-weight: 500;
  letter-spacing: 0.16em;
  text-transform: uppercase;
  opacity: 0;
  animation: rise-in 1s var(--ease) 1.65s forwards;
}

.hero__meta-line {
  width: 2.5rem;
  height: 1px;
  background: var(--line);
}

.hero__scroll {
  position: absolute;
  bottom: 0;
  left: clamp(1.5rem, 3.8vw, 4rem);
  display: flex;
  flex-direction: column;
  align-items: center;
  gap: 0.8rem;
  color: rgba(255, 255, 255, 0.5);
  font-size: 0.58rem;
  font-weight: 500;
  letter-spacing: 0.16em;
  text-transform: uppercase;
  opacity: 0;
  animation: rise-in 1s var(--ease) 1.7s forwards;
}

.hero__scroll-line {
  display: block;
  width: 1px;
  height: 48px;
  overflow: hidden;
  background: var(--line);
}

.hero__scroll-line::after {
  display: block;
  width: 1px;
  height: 48px;
  background: rgba(255, 255, 255, 0.8);
  content: "";
  animation: scroll-line 2s ease-in-out infinite;
}

.manifesto {
  position: relative;
  padding: clamp(6rem, 10vw, 9rem) clamp(1.5rem, 8.3vw, 8rem);
  overflow: hidden;
  background:
    radial-gradient(circle at 85% 18%, rgba(190, 31, 52, 0.12), transparent 24%),
    linear-gradient(145deg, #f3f0ea 0%, #e8e4dc 100%);
  color: #10151c;
}

.section-kicker {
  margin-bottom: 2rem;
  color: #a71f31;
  font-size: 0.7rem;
  font-weight: 600;
  letter-spacing: 0.2em;
  text-transform: uppercase;
}

.manifesto h2 {
  max-width: 900px;
  margin: 0;
  font-size: clamp(3.5rem, 8vw, 8.5rem);
  font-weight: 300;
  letter-spacing: -0.07em;
  line-height: 0.92;
}

.manifesto__copy {
  max-width: 510px;
  margin: 3rem 0 0 auto;
  color: #4d555f;
  font-size: clamp(1.05rem, 1.5vw, 1.35rem);
  line-height: 1.55;
}

.science-grid {
  display: grid;
  grid-template-columns: 1.35fr 1fr 1fr;
  gap: 1px;
  margin-top: clamp(4rem, 7vw, 6.5rem);
  background: rgba(16, 21, 28, 0.14);
}

.science-card {
  display: flex;
  min-height: 340px;
  flex-direction: column;
  justify-content: space-between;
  padding: clamp(1.4rem, 2.5vw, 2.5rem);
  background: #ece8e1;
  transition: background 400ms ease, color 400ms ease;
}

.science-card:hover { color: #fff; background: #111923; }
.science-card--lead { color: #fff; background: #111923; }
.science-card__number { color: #b32538; font-size: 0.65rem; }
.science-card div > p:first-child { color: #a92335; font-size: 0.62rem; letter-spacing: 0.16em; text-transform: uppercase; }
.science-card h3 { margin: 0.7rem 0; font-size: clamp(1.4rem, 2.2vw, 2.25rem); font-weight: 400; letter-spacing: -0.045em; line-height: 1.05; }
.science-card__body { max-width: 290px; color: #6c7278; font-size: 0.86rem; line-height: 1.6; }
.science-card:hover .science-card__body { color: rgba(255,255,255,.58); }
.science-card a { display: inline-flex; gap: 1rem; margin-top: 2rem; font-size: 0.74rem; }

.areas {
  padding: clamp(6rem, 10vw, 10rem) clamp(1.5rem, 8.3vw, 8rem);
  background: #08121e;
}

.areas__header {
  display: grid;
  grid-template-columns: 1.7fr 1fr;
  align-items: end;
  gap: 4rem;
}

.areas__header h2,
.stories__header h2 {
  margin: 0;
  font-size: clamp(3.4rem, 7vw, 7.8rem);
  font-weight: 300;
  letter-spacing: -0.07em;
  line-height: 0.93;
}

.areas__header > p {
  max-width: 430px;
  margin: 0 0 0.8rem;
  color: rgba(255, 255, 255, 0.56);
  line-height: 1.7;
}

.area-explorer {
  display: grid;
  grid-template-columns: minmax(260px, 0.72fr) 2fr;
  gap: 1px;
  margin-top: clamp(4rem, 8vw, 7rem);
  background: rgba(255,255,255,.14);
}

.area-tabs {
  display: flex;
  flex-direction: column;
  background: #08121e;
}

.area-tabs button {
  display: flex;
  align-items: center;
  justify-content: space-between;
  flex: 1;
  min-height: 76px;
  padding: 1.25rem 1.5rem;
  border: 0;
  border-bottom: 1px solid rgba(255,255,255,.12);
  color: rgba(255,255,255,.48);
  background: transparent;
  font: inherit;
  font-size: .83rem;
  text-align: left;
  cursor: pointer;
  transition: color 250ms ease, background 250ms ease, padding 350ms var(--ease);
}

.area-tabs button:hover,
.area-tabs button[aria-selected="true"] {
  padding-left: 2rem;
  color: #fff;
  background: rgba(255,255,255,.055);
}

.area-tabs button[aria-selected="true"] { box-shadow: inset 3px 0 0 var(--red); }
.area-tabs button span { color: rgba(255,255,255,.28); font-size: .58rem; }

.area-panel {
  position: relative;
  display: grid;
  min-height: 580px;
  grid-template-columns: 1.15fr 1fr;
  overflow: hidden;
  background: #101d29;
}

.area-panel__index {
  position: absolute;
  z-index: 2;
  top: 1.5rem;
  right: 1.5rem;
  color: rgba(255,255,255,.4);
  font-size: .58rem;
  letter-spacing: .14em;
}

.area-panel__visual {
  position: relative;
  overflow: hidden;
  background:
    radial-gradient(circle at 45% 45%, var(--area-glow, rgba(216,34,56,.72)), transparent 7%),
    radial-gradient(circle at 50% 50%, var(--area-fade, rgba(180,30,52,.28)), transparent 38%),
    #07111b;
}

.area-panel__visual::before,
.area-panel__visual::after,
.area-panel__visual span {
  position: absolute;
  inset: 50%;
  width: 53%;
  aspect-ratio: 1;
  border: 1px solid rgba(255,255,255,.22);
  border-radius: 44% 56% 61% 39% / 46% 38% 62% 54%;
  content: "";
  transform: translate(-50%,-50%) rotate(18deg);
  animation: area-organic 12s ease-in-out infinite;
}

.area-panel__visual::after { width: 72%; opacity: .5; animation-delay: -4s; }
.area-panel__visual span { width: 34%; opacity: .68; animation-delay: -8s; }
.area-panel__content { align-self: end; padding: clamp(2rem, 5vw, 5rem); }
.area-panel__label { color: var(--red); font-size: .62rem; letter-spacing: .16em; text-transform: uppercase; }
.area-panel__content h3 { margin: .7rem 0 1.4rem; font-size: clamp(2.6rem, 5vw, 5.5rem); font-weight: 300; letter-spacing: -.065em; }
.area-panel__content > p:not(.area-panel__label) { max-width: 430px; color: rgba(255,255,255,.58); line-height: 1.7; }
.area-panel__content a { display: inline-flex; gap: 1rem; margin-top: 2rem; padding-bottom: .5rem; border-bottom: 1px solid rgba(255,255,255,.28); font-size: .75rem; }

.focus-strip {
  display: grid;
  grid-template-columns: repeat(4, 1fr);
  background: #d1273d;
}

.focus-strip div {
  min-height: 230px;
  padding: 2.4rem;
  border-right: 1px solid rgba(255,255,255,.18);
}

.focus-strip strong { display: block; font-size: clamp(2.8rem, 5vw, 5rem); font-weight: 300; letter-spacing: -.07em; }
.focus-strip span { display: block; max-width: 160px; margin-top: 2rem; color: rgba(255,255,255,.7); font-size: .72rem; line-height: 1.5; }

.patients {
  display: grid;
  min-height: clamp(720px, 78svh, 940px);
  grid-template-columns: 1fr 1fr;
  background: #07111d;
}

.patients__visual {
  position: relative;
  display: grid;
  place-items: center;
  min-height: clamp(720px, 78svh, 940px);
  overflow: hidden;
  background: radial-gradient(circle at center, #182b3d 0%, #09131f 48%, #030a12 100%);
}

.patients__orb {
  width: min(42vw, 520px);
  aspect-ratio: 1;
  border-radius: 50%;
  background: radial-gradient(circle at 38% 34%, #eff5f7 0%, #8ca5b1 13%, #243e50 42%, #07111c 72%);
  box-shadow: inset -45px -40px 100px rgba(0,0,0,.65), 0 0 100px rgba(120,166,190,.14);
}

.patients__rings,
.patients__rings span { position: absolute; inset: 50%; }
.patients__rings span {
  width: min(48vw, 600px);
  aspect-ratio: 1;
  border: 1px solid rgba(216, 234, 244, 0.16);
  border-radius: 50%;
  transform: translate(-50%, -50%);
  animation: ring 7s ease-in-out infinite;
}
.patients__rings span:nth-child(2) { width: min(57vw, 700px); animation-delay: -2.3s; }
.patients__rings span:nth-child(3) { width: min(68vw, 820px); animation-delay: -4.6s; }
.patients__visual > p { position: absolute; right: 2.5rem; bottom: 2rem; left: 2.5rem; display: flex; justify-content: space-between; color: rgba(255,255,255,.4); font-size: .58rem; letter-spacing: .18em; text-transform: uppercase; }

.patients__content {
  display: flex;
  flex-direction: column;
  justify-content: center;
  padding: clamp(5rem, 9vw, 9rem);
}

.patients__content h2,
.about__header h2,
.closing h2 { margin: 0; font-size: clamp(3.1rem, 5.7vw, 6.6rem); font-weight: 300; letter-spacing: -0.07em; line-height: .94; }
.patients__content > p:not(.section-kicker) { max-width: 520px; margin: 2.5rem 0; color: rgba(255,255,255,.58); font-size: 1rem; line-height: 1.7; }
.dark-link { display: inline-flex; align-items: center; gap: 1rem; width: fit-content; padding-bottom: .5rem; border-bottom: 1px solid rgba(255,255,255,.3); font-size: .78rem; }

.stories {
  padding: clamp(6rem, 10vw, 10rem) clamp(1.5rem, 8.3vw, 8rem);
  background: #ece9e2;
  color: #111820;
}

.stories__header {
  display: flex;
  align-items: end;
  justify-content: space-between;
  gap: 2rem;
}

.stories__header > a,
.about__link {
  display: inline-flex;
  gap: 1rem;
  padding-bottom: .6rem;
  border-bottom: 1px solid rgba(17,24,32,.3);
  font-size: .75rem;
}

.story-grid {
  display: grid;
  grid-template-columns: 1.15fr 1fr 1fr;
  gap: 1.2rem;
  margin-top: clamp(4rem, 8vw, 7rem);
}

.story-card {
  min-width: 0;
  background: #f5f2ec;
  transition: transform 450ms var(--ease), box-shadow 450ms var(--ease);
}

.story-card:hover { transform: translateY(-8px); box-shadow: 0 24px 50px rgba(17,24,32,.12); }
.story-card__art { position: relative; min-height: 330px; overflow: hidden; }
.story-card--red .story-card__art { background: radial-gradient(circle at 70% 30%, #ff788a, transparent 15%), linear-gradient(145deg,#6d0b1a,#e72b44); }
.story-card--blue .story-card__art { background: radial-gradient(circle at 40% 45%, #b8e4ed, transparent 14%), linear-gradient(145deg,#071b2c,#32637a); }
.story-card--silver .story-card__art { background: radial-gradient(circle at 70% 35%, #fff, transparent 13%), linear-gradient(145deg,#4e5760,#dce3e5); }
.story-card__wave { position: absolute; inset: 17% -10%; border: 1px solid rgba(255,255,255,.42); border-radius: 50%; transform: rotate(-18deg); box-shadow: 0 0 70px rgba(255,255,255,.18); }
.story-card__cell { position: absolute; top: 50%; left: 50%; width: 52%; aspect-ratio: 1; border: 1px solid rgba(255,255,255,.55); border-radius: 44% 56% 47% 53%; box-shadow: inset 0 0 50px rgba(172,232,242,.24); transform: translate(-50%,-50%) rotate(22deg); }
.story-card__lens { position: absolute; top: 17%; right: 12%; width: 46%; aspect-ratio: 1; border-radius: 50%; background: linear-gradient(145deg,rgba(255,255,255,.8),rgba(255,255,255,.03)); box-shadow: -60px 90px 0 rgba(10,22,34,.18); }
.story-card__copy { min-height: 235px; padding: 1.7rem; }
.story-card__copy p { color: #a92335; font-size: .58rem; letter-spacing: .16em; text-transform: uppercase; }
.story-card__copy h3 { margin: 1rem 0 2rem; font-size: clamp(1.5rem, 2.3vw, 2.3rem); font-weight: 400; letter-spacing: -.045em; line-height: 1.08; }
.story-card__copy > span { color: #697078; font-size: .7rem; }

.about {
  padding: clamp(6rem, 9vw, 8rem) clamp(1.5rem, 8.3vw, 8rem);
  background: #f3f0ea;
  color: #111820;
}

.about__header { display: grid; grid-template-columns: 1fr 2fr; column-gap: 5vw; }
.about__header .section-kicker { grid-row: span 2; }
.about__header > p:last-child { max-width: 470px; margin: 2.5rem 0 0; color: #626970; line-height: 1.65; }
.company-stats { display: grid; grid-template-columns: repeat(4, 1fr); gap: 1px; margin-top: clamp(4.5rem, 7vw, 6.5rem); background: rgba(16,21,28,.15); }
.company-stats article { min-height: 260px; padding: 2rem; background: #f3f0ea; }
.company-stats strong { display: block; margin-top: 2.5rem; font-size: clamp(2.5rem,4vw,4.4rem); font-weight: 300; letter-spacing: -.065em; }
.company-stats p { max-width: 220px; margin-top: 2rem; color: #697078; font-size: .78rem; line-height: 1.55; }
.about__link { margin-top: 3rem; }

.careers {
  display: grid;
  min-height: clamp(720px, 78svh, 940px);
  grid-template-columns: 1.08fr 1fr;
  background: #0a1420;
}

.careers__copy { align-self: center; padding: clamp(5rem, 9vw, 9rem); }
.careers__copy h2 { margin: 0; font-size: clamp(3.4rem, 7vw, 7.5rem); font-weight: 300; letter-spacing: -.075em; line-height: .91; }
.careers__copy > p:not(.section-kicker) { max-width: 480px; margin: 2.4rem 0; color: rgba(255,255,255,.58); line-height: 1.7; }
.careers__art { position: relative; min-height: clamp(720px, 78svh, 940px); overflow: hidden; background: radial-gradient(circle at 50% 40%,#314b5e,#0b1723 50%,#050c14); }
.careers__art::before { position: absolute; inset: 12%; border: 1px solid rgba(255,255,255,.16); border-radius: 50%; content:""; }
.careers__art span { position: absolute; top: 50%; left: 50%; width: 18%; aspect-ratio:1; border-radius:50%; background: radial-gradient(circle at 38% 30%,#fff,#b1c6d0 12%,#29485e 42%,#07111b 75%); box-shadow: 0 0 70px rgba(164,211,228,.18); transform:translate(-50%,-50%); }
.careers__art span:nth-child(2) { top: 27%; left: 68%; width: 11%; opacity:.58; }
.careers__art span:nth-child(3) { top: 76%; left: 30%; width: 8%; opacity:.36; }

.closing {
  display: grid;
  min-height: clamp(620px, 68svh, 800px);
  place-content: center;
  justify-items: center;
  padding: 6rem 1.5rem;
  text-align: center;
  background: radial-gradient(circle at 50% 45%, rgba(211,36,58,.18), transparent 27%), #030a13;
}
.closing .section-kicker { color: rgba(255,255,255,.48); }
.button--closing { min-width: 220px; min-height: 60px; padding: .8rem 1.2rem .8rem 1.6rem; border: 1px solid rgba(255,255,255,.24); border-radius: 999px; background: rgba(255,255,255,.05); }
.button--closing:hover { background: var(--red); border-color: var(--red); }
.closing__actions { display:flex; align-items:center; gap:2rem; margin-top:3rem; }

.footer { padding: 3rem clamp(1.5rem, 5vw, 5rem) 1.5rem; border-top: 1px solid rgba(255,255,255,.12); background: #030a13; }
.footer__top { display:grid; grid-template-columns:.8fr 1.3fr auto; align-items:start; gap:3rem; padding-bottom:2.5rem; border-bottom:1px solid rgba(255,255,255,.12); }
.footer__top > p { max-width:450px; margin:0; color:rgba(255,255,255,.48); font-size:.82rem; line-height:1.6; }
.footer__toplink { color:rgba(255,255,255,.6); font-size:.7rem; }
.footer__nav { display:grid; grid-template-columns:repeat(3,1fr); gap:3rem; max-width:760px; margin:2.5rem 0 3rem auto; }
.footer__nav div { display:flex; flex-direction:column; gap:.75rem; }
.footer__nav p { margin:0 0 .6rem; color:rgba(255,255,255,.3); font-size:.58rem; letter-spacing:.16em; text-transform:uppercase; }
.footer__nav a { color:rgba(255,255,255,.68); font-size:.74rem; }
.footer__nav a:hover { color:#fff; }
.footer__bottom { display:flex; justify-content:space-between; gap:2rem; padding-top:1.5rem; border-top:1px solid rgba(255,255,255,.12); }
.footer__bottom p { margin:0; color:rgba(255,255,255,.32); font-size:.58rem; }

.reveal-section > * { transition: opacity 1s var(--ease), transform 1s var(--ease); }

@keyframes scene-in {
  from { opacity: 0; transform: scale(1.13); filter: blur(10px); }
  to { opacity: 1; transform: scale(1.035); filter: blur(0); }
}

@keyframes fade-down {
  from { opacity: 0; transform: translateY(-12px); }
  to { opacity: 1; transform: translateY(0); }
}

@keyframes title-reveal {
  to { transform: translateY(0); }
}

@keyframes rise-in {
  to { opacity: 1; transform: translateY(0); }
}

@keyframes pulse {
  0% { opacity: 0.85; transform: translate(-50%, -50%) scale(0.15); }
  75%, 100% { opacity: 0; transform: translate(-50%, -50%) scale(2.9); }
}

@keyframes core-breathe {
  0%, 100% { opacity: 0.8; transform: translate(-50%, -50%) scale(0.8); }
  50% { opacity: 1; transform: translate(-50%, -50%) scale(1.15); }
}

@keyframes scroll-line {
  from { transform: translateY(-100%); }
  to { transform: translateY(100%); }
}

@keyframes ring {
  0%, 100% { opacity: .28; transform: translate(-50%, -50%) scale(.96); }
  50% { opacity: .8; transform: translate(-50%, -50%) scale(1.035); }
}

@keyframes area-organic {
  0%,100% { border-radius:44% 56% 61% 39% / 46% 38% 62% 54%; transform:translate(-50%,-50%) rotate(18deg) scale(.96); }
  50% { border-radius:58% 42% 35% 65% / 38% 57% 43% 62%; transform:translate(-50%,-50%) rotate(38deg) scale(1.05); }
}

@media (max-width: 900px) {
  .hero__image {
    background-position: 63% center;
  }

  .hero__veil {
    background:
      linear-gradient(90deg, rgba(2, 8, 18, 0.94) 0%, rgba(2, 8, 18, 0.72) 47%, rgba(2, 8, 18, 0.16) 100%),
      linear-gradient(180deg, rgba(2, 8, 18, 0.28), transparent 40%, rgba(2, 8, 18, 0.58));
  }

  .hero__content {
    width: min(660px, 72vw);
    margin-left: clamp(1.5rem, 7vw, 4rem);
  }

  .nav__links {
    display: none;
  }

  .science-grid { grid-template-columns: 1fr; }
  .science-card { min-height: 260px; }
  .areas__header { grid-template-columns:1fr; }
  .area-explorer { grid-template-columns:1fr; }
  .area-tabs { display:grid; grid-template-columns:repeat(5,1fr); overflow-x:auto; }
  .area-tabs button { min-width:150px; }
  .area-panel { min-height:660px; }
  .focus-strip { grid-template-columns:repeat(2,1fr); }
  .story-grid { grid-template-columns:1fr 1fr; }
  .story-card:first-child { grid-column:1 / -1; }
  .patients { grid-template-columns: 1fr; }
  .patients { min-height: auto; }
  .patients__visual { min-height: 620px; }
  .patients__orb { width: min(72vw, 500px); }
  .patients__content { padding: 6rem clamp(1.5rem, 7vw, 4rem); }
  .about__header { grid-template-columns: 1fr; }
  .about__header .section-kicker { grid-row: auto; }
  .company-stats { grid-template-columns:repeat(2,1fr); }
  .careers { grid-template-columns:1fr; }
  .careers { min-height:auto; }
  .careers__art { min-height:600px; }
}

@media (max-width: 620px) {
  .hero {
    min-height: 780px;
  }

  .nav {
    padding: 1.35rem 1.25rem;
  }

  .hero__image {
    background-position: 65% 44%;
    transform: translate3d(0, 0, 0) scale(1.15);
  }

  .hero__veil {
    background:
      linear-gradient(180deg, rgba(2, 8, 18, 0.38) 0%, rgba(2, 8, 18, 0.2) 30%, rgba(2, 8, 18, 0.96) 76%, #020812 100%),
      linear-gradient(90deg, rgba(2, 8, 18, 0.52), rgba(2, 8, 18, 0.05));
  }

  .hero__pulse {
    top: 45%;
    left: 54%;
  }

  .brand__descriptor {
    display: none;
  }

  .hero__content {
    align-self: end;
    width: auto;
    margin: 0;
    padding: 19rem 1.25rem 7rem;
  }

  .eyebrow {
    margin-bottom: 1.25rem;
  }

  h1 {
    font-size: clamp(3.1rem, 15vw, 4.5rem);
  }

  .hero__lede {
    max-width: 94%;
    margin-top: 1.25rem;
    font-size: 0.98rem;
    line-height: 1.5;
  }

  .hero__actions {
    align-items: flex-start;
    flex-direction: column;
    gap: 1.25rem;
    margin-top: 1.5rem;
  }

  .button--primary {
    min-width: min(100%, 230px);
  }

  .hero__meta,
  .hero__scroll {
    display: none;
  }

  .manifesto {
    padding: 6rem 1.25rem 8rem;
  }

  .manifesto__copy {
    margin-top: 2rem;
  }

  .menu-panel { padding-right: 1.25rem; padding-left: 1.25rem; }
  .menu-panel__inner a { font-size: 3rem; }
  .patients__visual { min-height: 520px; }
  .patients__visual > p { right: 1.25rem; left: 1.25rem; }
  .patients__content { padding: 5rem 1.25rem; }
  .about { padding: 5rem 1.25rem; }
  .area-panel { grid-template-columns:1fr; min-height:760px; }
  .area-panel__visual { min-height:390px; }
  .focus-strip { grid-template-columns:1fr 1fr; }
  .focus-strip div { min-height:190px; padding:1.5rem; }
  .story-grid { grid-template-columns:1fr; }
  .story-card:first-child { grid-column:auto; }
  .story-card__art { min-height:280px; }
  .stories__header { align-items:flex-start; flex-direction:column; }
  .company-stats { grid-template-columns:1fr; margin-top:5rem; }
  .company-stats article { min-height:210px; }
  .careers__copy { padding:5rem 1.25rem; }
  .careers__art { min-height:480px; }
  .closing__actions { align-items:center; flex-direction:column; }
  .footer__top { grid-template-columns:1fr; gap:2rem; }
  .footer__nav { grid-template-columns:1fr 1fr; margin-left:0; }
  .footer__bottom { flex-direction:column; }
}

@media (prefers-reduced-motion: reduce) {
  html { scroll-behavior: auto; }
  *, *::before, *::after {
    animation-duration: 0.01ms !important;
    animation-delay: 0ms !important;
    animation-iteration-count: 1 !important;
    transition-duration: 0.01ms !important;
  }
  .hero__backdrop { transform: none; }
  .title-line > span { transform: none; }
  .eyebrow, .hero__lede, .hero__actions, .hero__meta, .hero__scroll, .nav { opacity: 1; }
}